这一切都在DNA中

MD安德森科学家可能已经发现了为什么有些brain cancerpatients develop resistance to standard treatments.

Enhanced DNA repair, which allows damaged or mutated cancer cells to repair themselves, can enable glioblastoma, the most common and aggressive type of brain cancer, to progress more quickly.

“有效治疗的主要障碍是获得治疗的抵抗力，”Wei Zhang, Ph.D.，教授病理. “Enhanced DNA repair can allow these cancer cells to survive, contributing to resistance and tumor recurrence.”

张的团队已经确定了Aktr3作为癌症，可以“强大”刺激胶质瘤进展。调查结果发表在国家科学院的诉讼程序中。

The study was funded by the National Institutes of Health, the National Cancer Institute, the Goldhirsh Foundation, the Academy of Finland, the Sigrid Juselius Foundation, and the Finnish Funding Agency for Technology and Innovation.