希布勒没有在厨房工作,而是在德克萨斯州史密斯维尔的MD安德森科学园的实验室里工作。她的工具包括试管、孵化器和烧杯。
希布勒的父母都是学校教师,当她去波士顿的萨福克大学(Suffolk University)获得生物学学士学位时,她本想成为一名海洋生物学家。但在哈佛医学院/马萨诸塞州总医院实习期间,她迷上了分子生物学。
“在了解了MD Anderson之后,我申请了GSBS(生物医学科学研究生院)……并于2007年8月搬到了休斯顿。我从来没有这么热过,”她说。
希布勒与几名MD安德森的科学家轮流在GSBS培训学生。GSBS是由MD安德森和德克萨斯大学休斯顿健康科学中心联合运营的。当莎伦·登特博士,当时的生物化学和分子生物学教授同意做她的导师时,她很高兴。
酵母模仿基因突变
邓特在2010年年中被任命为分子癌变学系主任后,将她的实验室搬到了科学园,希布勒几个月后也搬到了那里。另外两名GSBS学生是登特实验室的成员。
“用酵母作为模型,我模拟了一些白血病患者中存在的与不良预后相关的基因突变。通过研究基因在突变细胞和正常细胞中的功能,我对正常细胞的行为以及基因突变时会发生什么有了更清晰的认识,”Schibler说。她的研究乐动体育LDsports中国得到了Schissler基金会奖学金的支持。
她最近开始与MD安德森的一位资深白血病专家合作,看看她的研究是否有助于改善患者的诊断和治疗。乐动体育LDsports中国
”博士。登特给了我们灵活性和独立性来检验我们的想法并科学地发展,”希布勒说。“我热爱我的工作。”
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