休斯顿卫理公会医院,MD安德森癌症中心团队执行第一个多器官移植,包括头骨和头皮

MD安德森新闻发布2015年6月4日

手术团队从休斯顿卫理公会医院德克萨斯州大学安德森癌症中心在进行肾脏和胰腺移植的同时,首次成功移植,头皮和颅骨。

詹姆斯百胜,从德克萨斯州奥斯汀市55岁的软件开发者,是第一个病人接受与实体器官移植的同时颅面组织移植在一起。

“这一直很长的旅程,我非常感谢所有正在进行移植的医生,”博森说。“我惊讶于我的感受,我的感受多么伟大,我永远感激我有另一个机会回到做我所爱的事情,也是我所爱的人。”

The 15-hour surgery, which was conceptualized nearly four years ago, was performed at Houston Methodist Hospital by a team led by MD Anderson’s Jesse C. Selber, M.D., and Houston Methodist’s A. Osama Gaber, M.D., on Friday, May 22, about 20 hours after LifeGift alerted the team to the availability of the organs.

今天博森将从休斯顿卫理公会医院出院。他将留在诺拉的休斯敦在诺拉的家中,从两家机构的协调后续处理的三周内。

超过50名医疗保健专业人员,协助或支持手术,包括来自MD Anderson和Houston Methodist医院的专门重建整形外科医生,以及一支移植外科医生,神经外科医生和来自休斯顿卫理公会的护士和其他人。救生员也在规划和准备中发挥了不可或缺的作用,从来没有促进采购头皮和头骨进行移植。

“While it was incredibly exciting to bring together two of the Texas Medical Center’s leading institutions to collaborate and leverage their expertise for this first-ever transplant, the most meaningful result is what the successful surgery will mean for Jim,” said Selber, associate professor of Plastic and Reconstructive Surgery at MD Anderson, the clinical team co-leader and the originator of the idea to transplant the scalp and skull during the same surgery to transplant the other organs. “This was an ideal clinical situation that allowed us to transplant all these tissues from one patient, and Jim’s patience, courage and enthusiasm for the idea were vital.”

“这是一个非常复杂的手术,因为我们不得不利用移植显微组织,”迈克尔Klebuc,医学博士,谁带领休斯顿卫理公会医院整形外科团队外科医生说。“想象一下,在显微镜下将血管连接1/16英寸,小针迹大约一半的人类头发的直径,用工具可以用来制作精细的瑞士手表。”

2006年,博森被诊断出患有Leiomyosarcoma,他的头皮上的平滑肌罕见的癌症。成功用化疗和辐射治疗,他的头部留下了大,深伤的伤口,其中包括头皮和他头骨的全部厚度向下他的大脑。

除了伤口外,这将需要重大重建的承诺,博伊森的肾脏和胰腺,首次于1992年移植,尚未发生。患有5岁的糖尿病患者,多年来博森的下降条件促使原来的双器移植。

当Selber和Boysen首次遇到时,头皮和颅骨伤口正在预防医生执行第二个固体器官移植。同样地,他的临危肾和胰腺功能与他的免疫抑制药物同样复杂化了头皮重建。

但是,虽然他的伤口,药物和移植器官衰竭产生了临床Catch-22,但它们也将成为导致三重移植的溶液的一部分。

“当我第一次见到吉姆,我提出需要一个新的肾脏和胰腺持续的抗排斥药物,以支持他们,并在将这些相同的药物进行保护的同时接收一个完整的头皮和颅骨移植他之间的连接塞尔伯说。“这是一个真正独特的临床局势,创造了执行这种复杂移植的机会。”

“With the Houston Methodist transplant resources, we had the perfect opportunity to help Mr. Boysen,” said Gaber, director of the Houston Methodist J.C. Walter Jr. Transplant Center and the surgeon who performed the kidney and pancreas transplants and led the Houston Methodist team who cared for Boysen. “I was pleased that, despite the difficult nature of the procedure, the donor and recipient surgeries worked flawlessly. The two surgeries spanned over 24 hours and required multiple Houston Methodist Hospital and MD Anderson physicians and Houston Methodist nursing teams to complete. Our nurses and transplant coordinators fell in love with Jim and were excited to see him do so well.”